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Список литературы

1. Fried, L.P. Frailty in older adults: evidence for a phenotype/L.P. Fried [et al.]//J. Gerontol. Med. Sci. - 2001. - Vol. 56 (3). - P. 146 - 156.

2. Mitnitski, A.B., Mogilner, A.J., Rockwood, K. Accumulation of deficits as a proxy measure of aging/A.B. Mitnitski, A.J. Mogilner, K. Rockwood//Scientific World J. - 2001. - Vol. 1. - P. 323 - 336.

3. Vermeiren S. et al. Frailty and the Prediction of Negative Health Outcomes: A Meta-Analysis. J Am Med Dir Assoc. 2016; 17(12): 1163.e1 - 1163.el7.

4. Weiss, O.C Frailty and Chronic Diseases in Older Adults/O.C. Weiss//Clin. Geriatr. Med. - 2011. - Vol. 27. - P. 39 - 52.

5. Clegg A. et al. Frailty in elderly people. The Lancet. 2013 Mar; 381(9868): 752 - 62

6. Collard, R.M. Prevalence of frailty in community dwelling older persons: a systematic review/R.M. Collard//J. Am. Geriatr. Soc. - 2012. - Vol. 60(8). - P. 1487 - 1492.

7. Kojima, G. Prevalence of frailty in nursing homes: A systematic review and metaanalysis/G. Kojima//J. Am. Med. Dir. Assoc. - 2015. - Vol. 16. - P. 940 - 945.

8. Gurina, N.A., Frolova, E.V., Degryse, J.M. A roadmap of aging in Russia: the prevalence of frailty in community-dwelling older adults in the St. Petersburg district - the "Crystal" study/J. Amer. Geriatr. Soc. - 2011. - Vol. 59 (6). - P. 980 - 988.

9. Остапенко, В.С. Распространенность и структура гериатрических синдромов у пациентов амбулаторно-поликлинических учреждений г.: авторефер. дис. канд. мед. наук/В.С. Остапенко; - М.: 2017. - 157 с.

10. Ткачева О.Н., Рунихина Н.К., Остапенко В.С., Шарашкина Н.В., Мхитарян Э.А., Онучина Ю.С., Лысенков С.Н. Валидация опросника для скрининга синдрома старческой астении в амбулаторной практике. Успехи геронтологии. 2017. Т. 30. N 2. С. 236 - 242.

11. 00000004.wmz M The relationship between frailty and polypharmacy in older people: A systematic review. Br J Clin Pharmacol. 2018. doi: 10.1111/bcp.13590.

12. Buta, B.J. Frailty assessment instruments: systematic characterization of the uses and contexts of highly - cited instruments/B.J. Buta [et al.]//Ageing Res. Rev. - 2016. - Vol. 26. - P. 53 - 61.

13. Morley JE, Arai H, Cao L, Dong B, Merchant RA, Vellas B, Visvanathan R, Woo J. Integrated Care: Enhancing the Role of the Primary Health Care Professional in Preventing Functional Decline: A Systematic Review. J Am Med Dir Assoc. 2017; 18(6): 489 - 494

14. Reflection paper on physical frailty: instruments for baseline characterisation of older populations in clinical trials. https://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2018/02/WC500244285.pdf

15. Syddall H. Et al. Is grip Strength a useful single marker of frailty?//Age and Ageing. - 2003. - Vol. 32. - N 6. - P. 650 - 656.

16. Borson S, Scanlan J, Brush M, Vitaliano P, Dokmak A. The Mini-Cog: a cognitive "vital signs" measure for dementia screening in multi-lingual elderly. Int J Geriatr Psychiatry 2000; 15: 1021 - 1027.

17. Borson S, Scanlan JM, Chen P, Ganguli M. The Mini-Cog as a screen for dementia: validation in a population-based sample. J Am Geriatr Soc 2003; 51: 1451 - 1454

18. Tsoi KK, Chan JY, Hirai HW, Wong SY, Kwok TC. Cognitive tests to detect dementia: a systematic review and meta-analysis. JAMA Intern Med 2015; 175: 1450 - 1458.

19. Бойцов С.А., Драпкина О.М., Калинина А.М., Ипатов П.В., Вергазова Э.К., Гамбарян М.Г., Еганян Р.А., Карамнова Н.С., Горный Б.Э., Егоров В.А., Соловьева С.Б., Старинский В.В., Бунова А.С., Ткачева О.Н., Рунихина Н.К., Котовская Ю.В., Мхитарян Э.А. "Организация проведения диспансеризации определенных групп взрослого населения". Методические рекомендации по практической реализации приказа Минздрава России от 26 октября 2017 г., N 869н "Об утверждении порядка проведения диспансеризации определенных групп взрослого населения". М. 2017 - 162 с. Утверждены главным специалистом по профилактической медицине Минздрава России 27 декабря 2017 г. Интернет-ресурсы: http://www.gnicpm.ru; http://ropniz.ru

20. Ramani L, Furmedge DS, Reddy SP. Comprehensive geriatric assessment. Br J Hosp Med Lond Engl 2005. 2014 Aug; 75 Suppl 8: C122 - 125.

21. British Geriatrics Society. Fit for Frailty Consensus best practice guidance for the care of older people living with frailty in community and outpatient settings [Internet]. 2014 Jun. Available from: http://www.bgs.org.uk/campaigns/fff/fff_full.pdf

22. Полипрагмазия в клинической практике: проблема и решения/под общей редакцией Д.А. Сычева, Спб.: ЦОП "Профессия", 2016 - 224 с.

23. Naples J.G., Handler S.M., Maher R.L. et.al. Geriatric Pharmacotherapy and Polypharmacy. In: Fillit H.M., Rockwood K., Young J.B. Brocklehurst's Textbook of Geriatric Medicine and Gerontology. 8th ed. Elsevier 2017; 849 - 854

24. Kanis JA, McCloskey EV, Johansson H, Oden A 00000005.wmz F, Strom O Development and use of 00000006.wmz in osteoporosis. Osteoporosis International. 2010; 21 Suppl 2: S407 - 13.

25. Dent E, Visvanathan R, Piantadosi C, Chapman I. Use of the Mini Nutritional Assessment to detect frailty in hospitalised older people. J Nutr Health Aging. 2012; 16(9): 764 - 7

26. Guigoz, Y., Vellas, B., Garry, P.J. Mini Nutritional Assessment: a practical assessment tool for grading the nutritional state of elderly patients/Y. Guigoz, B. Vellas, P.J. Garry//Facts Res. Gerontol. - 1994. - Vol. 2. - P. 15 - 59.

27. Inzitari, M. Gait speed predicts decline in attention and psychomotor speed in older adults: the health aging and body composition study/M. Inzitari [et al.]//Neuroepidemiology. - 2007. - Vol. 29(3-4). - P. 156 - 162.

28. Montero-Odasso, M. Gait velocity as a single predictor of adverse events in healthy seniors aged 75 years and older/M. Montero-Odasso [et al.]//J. Gerontol. A Biol. Sci. Med. Sci. - 2005. - Vol. 60(10). - P. 1304 - 1309.

29. Shinkai, S. Walking speed as a good predictor for the onset of functional dependence in a Japanese rural community population/S. Shinkai [et al.]//Age Ageing. - 2000. - Vol. 29(5). - P. 441 - 446.

30. Studenski, S. Gait speed and survival in older adults/S. Studenski [et al.]//J.A.M.A. - 2011. - Vol. 305(1). P. 50 - 58.

31. Mahoney, F., Barthel, D. Functional evaluation: the Barthel Index/F. Mahoney, D. Barthel//Md. State Med. J. - 1965. - Vol. 14. - P. 61 - 65

32. Lawton, M.P., and Brody, E.M. "Assessment of older people: Self-maintaining and instrumental activities of daily living." Gerontologist 1969; 9: 179 - 186

33. Bohannon RW. Reference values for the Timed Up and Go Test: A Descriptive Meta-Analysis. Journal of Geriatric Physical Therapy, 2006; 29(2): 64 - 8

34. Morse, J.M., Morse, R., & Tylko, S. Development of a scale to identify the fall-prone patient. Canadian Journal on Aging. 1989; 8: 366 - 377.

35. Shumway-Cook A, Brauer S, Woollacott M. Predicting the probability for falls in community-dwelling older adults using the timed up & go test. Phys Ther. 2000; 80: 896 - 903.

36. Kristensen MT, Foss NB, Kehlet H. Timed "Up and Go" Test as a predictor of falls within 6 months after hip fracture surgery. Phys Ther. 2007. 87(1): 24 - 30.

37. Eagle, J., Salamara, S., Whitman, D., Evans, L.A., Ho, E., & Olde, J. Comparison of three instruments in predicting accidental falls in selected inpatients in a general teaching hospital. Journal of Gerontological Nursing, 1999; 25(7): 40 - 45.

38. Folstein, M.F., Folstein, S.E., McHugh, P.R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician/M.F. Folstein, S.E. Folstein, P.R. McHugh//J. Psychiatr. Res. - 1975. - Vol. 12. - P. 189 - 198.

39. Huntzinger, J.A. Clock drawing in the screening assessment of cognitive impairment in an ambulatory care setting: a preliminary report/J.A. Huntzinger [et al.]//Gen. Hosp. Psychiatry. - 1992. - Vol. 14(2). - P. 142 - 144

40. Nasreddine, Z.S. Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment/Z.S. Nasreddine [et al.]//J. Am. Geriatr. Soc. - \ 2005. - Vol. 53. - P. 695 - 699.

41. Dubois B, Slachevsky A, Litvan I, Pillon B. The FAB: a Frontal Assessment Battery at bedside. Neurology. 2000 Dec 12; 55(11): 1621 - 6

42. Bingham KS, Kumar S, Dawson DR, Mulsant BH, Flint AJ. A Systematic Review of the Measurement of Function in Late-Life Depression. Am J Geriatr Psychiatry. 2018; 26(1): 54 - 72. doi: 10.1016/j.jagp.2017.08.011.

43. Sivertsen H., 00000007.wmz G.H., Engedal K., Selbaek G., Helvik A. S. Depression and Quality of Life in Older Persons: A Review//Dement Geriatr Cogn Disord. 2015. Vol. 40 (5-6). P. 311 - 39.

44. Meeks T.W., Vahia I.V., Lavretsky H., Kulkarni G., Jeste D. A tune in "a minor" can "b major": a review of epidemiology, illness course, and public health implications of subthreshold depression in older adults. Research Report//J. Affect. Disord. 2011. Vol. 129. P. 126 - 142.\

45. Katon W.J., Lin E., Russo J., Unutzer J. Increased medical costs of a population based sample of depressed elderly patients//Arch. Gen. Psychiatry. 2003. Vol. 60. P. 897 - 903.

46. Sheikh, J.I., Yesavage, J.A. Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version/J.I. Sheikh, J.A. Yesavage//Clinical Gerontologist. - 1986. - Vol. 5. - P. 165 - 173

47. Н.В. Погосова, Т.В. Довженко, А.Г. Бабин, А.А. Курсаков, В.А. Выгодин Открытый доступ Только для подписчиков Русскоязычная версия опросников PHQ-2 и 9: чувствительность и специфичность при выявлении депрессии у пациентов общемедицинской амбулаторной практике//Кардиоваскулярная терапия и профилактика. Т 13 N 3 (2014)

48. Alexopoulos GA, Abrams RC, Young RC & Shamoian CA: Cornell scale for depressionin dementia. Biol Psych, 1988, 23: 271 - 284.

49. Ткачева О.Н. и соавт. Методические рекомендации по предупреждению жестокого обращения с пожилыми людьми в учреждениях здравоохранения. Методические указания. - М.: Российский национальный исследовательский медицинский университет имени Н.И. Пирогова. 2017 г. 25 с.

http://rgnkc.ru/images/pdf_documets/Zhestokoe_obrashenie_preduprezhdenie.pdf

50. Макушкин Е.В., Полищук Ю.И., Рунихина Н.К., Панченко Е.А. Выявление и профилактика жестокого обращения с пожилыми и престарелыми людьми в учреждениях здравоохранения и социальной защиты. Помощь жертвам жестокого обращения: Методические рекомендации. - М.: ФГБУ "НМИЦ ПН им. В.П. Сербского" Минздрава России. 2017. - 23 с.

51. Stevens PE, Levin A; Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members Ann Intern Med. 2013 Jun 4; 158(11): 825 - 30

52. 00000008.wmz G. Anemia in the frail, elderly patient. Clin Interv Aging. 2016; 11: 319 - 26

53. Beghe C, Wilson A, Ershler WB. Prevalence and Outcomes of Anemia in Geriatrics: A Systematic Review of the Literature. Am J Med 2004; 116(7A): 3 - 10.

54. Gaskell H, Derry S, Moore RA, McOuay HJ. Prevalence of anemia in older persons: systematic review. BMC Geriatrics 2008; 8:1.

55. Yeap BB, Alfonso H, Chubb SA, Walsh JP, Hankey GJ, Almeida OP, Flicker L. Higher free tyroxine levels are associated with frailty in older men: the Health in Men Study. Clin Endocrinol (Oxf). 2012 May; 76(5): 741-8.27

56. Maxwell CA, Yu F. Biological Processes and Biomarkers Related to Frailty in Older Adults: A State-of-the-Science Literature Review. 2018; 9:1099800418798047

57. Ritt M, 00000009.wmz J, Ritt JI et al. Operationalizing a frailty index using routine blood and urine tests. Clin Interv Aging. 2017; 12: 1029 - 1040

58. Feng Z, Lugtenberg M, Franse C et al. Risk factors and protective factors associated with incident or increase of frailty among community-dwelling older adults: A systematic review of longitudinal studies. PLoS One. 2017; 12(6): e0178383

59. Bjelakovic G, Gluud LL, Nikolova D, Whitfield K, Wetterslev J, Simonetti RG, Bjelakovic M, Gluud C Vitamin D supplementation for prevention of mortality in adults (Review). The Cochrane Library 2014; :CD007470. doi: 10.1002/14651858.CD007470.pub3

60. Rubenstein LZ, Josephson KR, Wieland GD, English PA, Sayre JA, Kane RL Effectiveness of a geriatric evaluation unit. A randomized clinical trial. N Engl J Med. 1984; 311(26): 1664 - 70.

61. Bachmann S, Finger C, Huss A, Egger M, Stuck AE, Clough-Gorr KM. Inpatient rehabilitation specifically designed for geriatric patients: systematic review and meta-analysis of randomised controlled trials. BMJ. 2010; 340: c1718.

62. Clarke R. et al. Screening for vitamin B-12 and folate deficiency in older persons//Am. J. Clin. Nutr. 2003; 77: 1241 - 1247.

63. Gould D. et al. Visual Analogue Scale (VAS). Journal of Clinical Nursing 2001; 10: 697 - 706

64. Huskisson EC. Measurement of pain. Lancet 1974; 2: 1127 - 31.

65. Downie WW, Leatham PA, Rhind VM, Wright V, Branco JA, Anderson JA. Studies with pain rating scales. Ann Rheum Dis 1978; 37: 378 - 81.

66. Scott J, Huskisson EC. Graphic representation of pain. Pain 1976; 2: 175 - 84

67. Joos E, Peretz A, Beguin S, et al. Reliability and reproducibility of visual analogue scale and numeric rating scale for therapeutic evaluation of pain in rheumatic patients. J Rheumatol 1991; 18: 1269 - 70

68. Warden V, Hurley AC, Volicer L. Development and psychometric evaluation of the Pain Assessment in Advanced Dementia (PAINAD) scale. J Am Med Dir Assoc. 2003; 4(1): 9 - 15.

69. Федеральные клинические рекомендации по диагностике и лечению остеоартроза Ассоциации ревматологов России (www.reumatolog.ru)

70. Salive ME. Multimorbidity in older adults. Epidemiol Rev. 2013; 35: 75 - 83.

71. Ткачева О.Н., Котовская Ю.В., Рунихина Н.К., Остапенко В.С. Кардиология. 2017. Т. 57. N 5. С. 5 - 9.

72. Chou C.H., Hwang C.L., Wu Y. T. Effect of Exercise on Physical Function, Daily Living Activities, and Quality of Life in the Frail Older Adults: A Meta-Analysis//Arch Phys Med Rehab. 2012. Vol. 93. P. 237 - 44.

73. Gine-Garriga M., Roque-Figuls M., Coll-Planas L. et al. Physical Exercise Interventions for Improving Performance-Based Measures of Physical Function in Community-Dwell ing, Frail Older Adults: A Systematic Review and Meta-Analysis//Arch Phys Med Rehabil. 2014. Vol. 95. P. 753 - 69.

74. Weening-Dijksterhuis E., de Greef M. H.G., Scherder E. J.A. et al. Frail Institutionalized Older Persons: A Comprehensive Review on Physical Exercise, Physical Fitness, Activ ities of Daily Living, and Ouality-of-Life//Am J Phys Med Rehab. 2011. Vol. 90. P. 156 - 68.

75. 00000010.wmz J, Cooke R, Bobrowicz-Campos E, Santana S, Marcucci M, Cano A, et al. Effectiveness of interventions to prevent pre-frailty and frailty progression in older adults: a systematic review. JBI Database System Rev Implement Rep 2018; 16(1): 140 - 232.

76. Izquierdo M., Lusa Cadore E. Muscle Power Training in the In stitutionalized Frail: A New Approach to Counteracting Functional Declines and Very Late-Life Disability//Curr Med Res Opin. 2014. Vol. 30. P. 1385 - 90.

77. AliS, Garcia JM. Sarcopenia, cachexia and aging: diagnosis, mechanisms and therapeutic options - a mini-review. Gerontology. 2014; 60(4): 294 - 305

78. Dewansingh P, Melse-Boonstra A, Krijnen WP, van der Schans CP, Jager-Wittenaar H, van den Heuvel EGHM. Supplemental protein from dairy products increases body weight and vitamin D improves physical performance in older adults: a systematic review and meta-analysis Nutr Res. 2018; 49: 1 - 22.

79. Gaffney-Stomberg E, Insogna KL, Rodriguez NR, Kerstetter JE. Increasing dietary protein requirements in elderly people for optimal muscle and bone health. J Am Geriatr Soc. 2009; 57(6): 1073 - 1079.

80. Morley JE, Argiles JM, Evans WJ, Bhasin S, Cella D, Deutz NE, et al. Nutritional recommendations for the management of sarcopenia. J Am Med Dir Assoc. 2010; 11: 391 - 6.

81. Paddon-Jones D, Rasmussen BB. Dietary protein recommendations and the prevention of sarcopenia. Curr Opin Clin Nutr Metab Care. 2009; 12: 86 - 90.

82. Calvani R, Miccheli A, Landi F, et al. Current nutritional recommendations and novel dietary strategies to manage sarcopenia. J Frailty Aging. 2013; 2(1): 38 - 53.

83. Bauer J.M., Biolo G., Cederholm T. et al. Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROTAGE study group//Journal of the American Medical Directors Association. 2013. Vol. 14 (8). P. 542 - 559.

84. Poscia A, Milovanovic S, La Milia DI, Duplaga M, Grysztar M, Landi F, Moscato U, Magnavita N, Collamati A, Ricciardi W. Effectiveness of nutritional interventions addressed to elderly persons: umbrella systematic review with meta-analysis. Eur J Public Health. 2018; 28(2): 275 - 283.

85. Arnal MA, Mosoni L, Boirie Y, et al. Protein pulse feeding improves protein retention in elderly women. Am J Clin Nutr. 1999; 69(6): 1202 - 1208.

86. Symons TB, Sheffield-Moore M, Wolfe RR, Paddon-Jones D. A moderate serving of high-quality protein maximally stimulates skeletal muscle protein synthesis in young and elderly subjects. J Am Diet Assoc. 2009; 109: 1582 - 6.

87. Kim Ch-O, Lee K-R. Preventive effect of protein-energy supplementation on the functional decline of frail older adults with low socioeconomic status: a community-based randomized controlled study. J Gerontol A Biol Sci Med Sci 2013; 68(3): 309 - 16.

88. Normandin E., Houston D.K., Nicklas B.J. Caloric restric tion for treatment of geriatric obesity: Do the benefits outweigh the risks?//Current Nutrition Reports. 2015. Vol. 4 (2). P. 143 - 155.

89. Mathus-Vliegen E.M.H. Prevalence, pathophysiology, health consequences and treatment options of obesity in the el derly: a guideline//Obesity facts. 2012. Vol. 5 (3). P. 460 - 483.

90. Freiberger E., Goisser S., Porzel S. et al. Sarcopenic obe sity and complex interventions with nutrition and exercise in community-dwelling older persons - a narrative review//Clinical Inter ventions in Aging. 2015.

91. Kuk JL, Ardern CI. Influence of age on the association between various measures of obesity and all-cause mortality. J Am Geriatr Soc 2009; 57: 2077 - 2084.

92. Roubenoff R. Sarcopenic obesity: the confluence of two epidemics. Obes Res 2004; 12: 887 - 88.

93. Stessman J, Jacobs JM, Ein-Mor E, Bursztyn M. Normal body mass index rather than obesity predicts greater mortality in elderly people: the Jerusalem longitudinal study. J Am Geriatr Soc 2009; 57: 2232 - 2238.

94. Schott AM, Cormier C, Hans D, Favier F, Hausherr E, Dargent-Molina P et al: How hip and whole-body bone mineral density predict hip fracture in elderly women: the EPIDOS Prospective Study. Osteoporos Int 1998; 8: 247 - 254.

95. Stenholm S, Harris TB, Rantanen T, Visser M, Kritchevsky SB, Ferrucci L. Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care 2008; 11: 693 - 70.

96. Gillespie L.D., Robertson M.C., Gillespie W.J. et al. Interventions for preventing falls in older people living in the community//Cochrane Database Syst Rev. 2012. Vol. 9.

97. Turner S., Arthur G., Lyons R.A. et al. Modification of the home environment for the reduction of injuries//The Cochrane Database of Systematic Reviews. 2011. (2), CD003600. doi:10. 1002/14651858.

98. Cumming R.G., Thomas M., Szonyi G. et al. Home visits by an occupational therapist for assessment and modification of environmental hazards: a randomized trial of falls prevention//Journal of the American Geriatrics Society. 1999. Vol. 47 (12). P. 1397 - 1402.

99. Spink M., Menz H.B., Fotoohabadi M.R. et al. Effectiveness of a multifaceted podiatry intervention to prevent falls in community-dwelling older people with disabling foot pain: a randomised controlled trial//British Medical Journal. 2011. 342:d3411. doi:10. 1136/bmj.d3411.

100. Menz H.B., Sherrington C. The Footwear Assessment Form: a reliable clinical tool to assess footwear characteristics of relevance to postural stability in older adults//Clinical Rehabilitation. 2000. Vol. 14 (6). P. 657 - 664.

101. Livingston G, Sommerlad A, Orgeta V, et al. Dementia prevention, intervention, and care. Lancet. 2017; 390(10113): 2673 - 2734

102. Smith-Ray RL Impact of Cognitive Training on Balance and Gait in Older Adults. J Gerontol B Psychol Sci Soc Sci. 2015; 70(3): 357 - 66.

103. Hill NT, Mowszowski L, Naismith SL, Chadwick VL, Valenzuela M, Lampit A. Computerized Cognitive Training in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis. Am J Psychiatry. 2017; 174(4): 329 - 340.

104. Ng TP, Feng L, Nyunt MS et al. Nutritional, physical, cognitive, and combination interventions and frailty reversal among older adults: a randomized controlled trial. Am J Med 2015; 128: 1225 - 36.

105. Lozupone M, Panza F, Piccininni M, Copetti M, Sardone R, Imbimbo BP, Stella E, D"Urso F, Rosaria Barulli M, Battista P, Grasso A, Tortelli R, Capozzo R, Coppola F, Isabel Abbrescia D, Bellomo A, Giannelli G, Quaranta N, Seripa D, Logroscino G. Social Dysfunction in Older Age and Relationships with Cognition, Depression, and Apathy: The GreatAGE Study. J Alzheimers Dis. 2018. doi: 10.3233/JAD-180466

106. Valtorta NK, Kanaan M, Gilbody S, Hanratty B. Loneliness, social isolation and risk of cardiovascular disease in the English Longitudinal Study of Ageing. Eur J Prev Cardiol. 2018 Aug 2:2047487318792696. doi: 10.1177/2047487318792696.

107. Chipps J, Jarvis MA, Ramlall S. The effectiveness of e-Interventions on reducing social isolation in older persons: A systematic review of systematic reviews. J Telemed Telecare. 2017; 23(10): 817 - 827.

108. Wilson M, Mair A, Dreischulte T, Witham MD, NHS Scotland Model of Care Polypharmacy Working Group Prescribing to fit the needs of older people the - NHS Scotland Polypharmacy Guidance. J R Coll Physicians Edinb. (2nd edition) 2015; 45(2): 108 - 113.

109. Onder G, Landi F, Fusco D, et al. Recommendations to prescribe in complex older adults: results of the CRIteria to assess appropriate Medication use among Elderly complex patients (CRIME) project. Drugs Aging. 2014; 31(1): 33 - 45.

110. Beaudart C, Buckinx F, Rabenda V, Gillain S, Cavalier E, Slomian J. et al. The effects of vitamin D on skeletal muscle strength, muscle mass, and muscle power: a systematic review and metaanalysis of randomized controlled trials. J Clin Endocrinol Metab. 2014; 99(ll): 4336 - 45.

111. 00000011.wmz O, Cavalier E, Buckinx F, Reginster JY.. Relevance of vitamin D in the pathogenesis and therapy of frailty. Curr Opin Clin Nutr Metab Care. 2017; 20(1): 26 - 9.

112. Bischoff-Ferrari HA, Dawson-Hughes B, Staehelin HB, Orav JE, Stuck AE, Theiler R, Wong JB, Egli A, Kiel DP, Henschkowski J. Fall prevention with supplemental and active forms of vitamin D: a meta-analysis of randomised controlled trials. BMJ. 2009; 339: b3692.

113. Дефицит витамина D у взрослых: Диагностика, лечение и профилактика/Клинические рекомендации 2015 г.

114. Zhao JG, Zeng XT, Wang J, Liu L. Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017; 318(24): 2466 - 2482.

115. Vriendt P, Peersman W, Florus A, Verbeke M, Van de Velde D. Improving health related quality of life and independence in community dwelling frail older adults through a clientcentred and activity-oriented program. A pragmatic randomized controlled trial. J Nutr Health Aging 2016; 20(1): 35 - 40.

116. Black DM, Cummings SR, Karpf DB et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. 1996; 348: 1535 - 1541.

117. Harris ST, Watts NB, Genant HK et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 1999; 282: 1344 - 1352.

118. Chesnut C, Skag A, Christiansen C et al. Effects of Oral Ibandronate Administered Daily or Intermittently on Fracture Risk in Postmenopausal Osteoporosis. J Bone Miner Res. 2004; 19(8): 1241 - 1249.

119. Cummings S, Martin J, McClung M et al. Denosumab for Prevention of Fractures in Postmenopausal Women With Osteoporosis. N Engl J Med. 2009 Aug 20; 361(8): 756 - 65.

120. Lyles KW, 00000012.wmz CS, Magaziner JS et al for the HORIZON Recurrent Fracture Trial* Zoledronic Acid and Clinical Fractures and Mortality after Hip Fracture. N Engl J Med. 2007; 357: 1799 - 1809

121. Langdahl B, Teglbjaerg C, Ho P et al. A 24-Month Study Evaluating the Efficacy and Safety of Denosumab for the Treatment of Men With Low Bone Mineral Density: Results From the ADAMO Trial. The Journal of Clinical Endocrinology & Metabolism. 2015; 100(4): 1335 - 1342.

122. Tsai J, Uihlein A, Burnett-Bowie S et al. Comparative Effects of Teriparatide, Denosumab, and Combination Therapy on Peripheral Compartmental Bone Density, Microarchitecture, and Estimated Strength: the DATA-HRpQCT Study. J Bone Miner Res. 2014; 30(1): 39 - 45.

123. Cohen H, Feussner JR, Weinberger M, Carnes M, Hamdy RC, Hsieh F, et al. A controlled trial of inpatient and outpatient geriatric evaluation and management. N Engl J Med 2002; 346(12): 905 - 12.

124. NICE guideline. Multimorbidity: clinical assessment and management. nice.org.uk/guidance/ng56 NICE

125. Benetos A, Bulpitt CJ, Petrovic M, Ungar A, Agabiti Rosei E, Cherubini A, Redon J, Grodzicki T, Dominiczak A, Strandberg T, Mancia G. An Expert Opinion From the European Society of Hypertension-European Union Geriatric Medicine Society Working Group on the Management of Hypertension in Very Old, Frail Subjects. Hypertension. 2016; 67(5): 820 - 5.

126. Ткачева О.Н., Рунихина Н.К., Котовская Ю.В., Шарашкина Н.В., Остапенко В.С. Лечение артериальной гипертонии у пациентов 80 лет и старше и пациентов со старческой астенией. Кардиоваскулярная терапия и профилактика. 2017. Т. 16. N 1. С. 8 - 21.

127. Odden MC, Covinsky KE, Neuhaus JM, Mayeda ER, Peralta CA, Haan MN. The association of blood pressure and mortality differs by selfreported walking speed in older Latinos. J Gerontol A Biol Sci Med Sci. 2012; 67: 977 - 983.

128. Ogliari G, Westendorp RG, Muller M, Mari D, Torresani E, Felicetta I, Lucchi T, Rossi PD, Sabayan B, de Craen AJ. Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study: role of functional and cognitive status. Age Ageing. 2015; 44: 932 - 937.

129. Benetos A, Labat C, Rossignol P, Fay R, Rolland Y, Valbusa F, Salvi P, Zamboni M, Manckoundia P, Hanon O, Gautier S. Treatment with multiple blood pressure medications, achieved blood pressure, and mortality in older nursing home residents: The PARTAGE Study. JAMA Intern Med. 2015; 175: 989 - 995

130. Mossello E, Pieraccioli M, Nesti N, Bulgaresi M, Lorenzi C, Caleri V, Tonon E, Cavallini MC, Baroncini C, Di Bari M, Baldasseroni S, Cantini C, Biagini CA, Marchionni N, Ungar A. Effects of low blood pressure in cognitively impaired elderly patients treated with antihypertensive drugs. JAMA Intern Med. 2015; 175: 578 - 585.

131. Garrison SR, Kolber MR, Korownyk CS, McCracken RK, Heran BS, Allan GM. Blood pressure targets for hypertension in older adults. Cochrane Database Syst Rev 2017; 8:CD011575

132. Angelousi A, Girerdb N, Benetos A, Frimat L, Gautier S, Weryha G, Boivin JM. Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis. J Hypertens 2014; 32: 1562 - 1571.

133. Mol A, Reijnierse EM, Bui Hoang PTS, et al. Orthostatic hypotension and physical functioning in older adults: A systematic review and meta-analysis. Ageing Res Rev. 2018; 48: 122 - 144.

134. Peters R et al Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: an integrated evidence review and analysis of a large older adult hypertensive cohort. European Heart Journal (2018) 00, 1 - 9

135. Ettehad D, Emdin CA, Kiran A, Anderson SG, Callender T, Emberson J, Chalmers J, Rodgers A, Rahimi K. Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis. Lancet 2016; 387: 957 - 967.

136. Thomopoulos C, Parati G, Zanchetti A. Effects of blood pressure lowering on outcome incidence in hypertension: 4. Effects of various classes of antihypertensive drugs-overview and meta-analyses. J Hypertens 2015; 33: 195 - 211.

137. Антитромботическая терапия в пожилом и старческом возрасте: согласованное мнение экспертов. Кардиоваскулярная терапия и профилактика//2017. - Т. 16 N 3. С. 4 - 33.

138. Marinigh R, Lip GY, Fiotti N, Giansante C, Lane DA. Age as a risk factor for stroke in atrial fibrillation patients: implications for thromboprophylaxis. J Am Coll Cardiol 2010; 56: 827 - 837.

139. Gage BF, Boechler M, Doggette AL, Fortune G, Flaker GC, Rich MW, Radford MJ. Adverse outcomes and predictors of underuse of antithrombotic therapy in medicare beneficiaries with chronic atrial fibrillation. Stroke 2000; 31: 822 - 827

140. Andreotti F, Rocca B, Husted S, Ajjan RA, Ten Berg J, Cattaneo M, Collet JP, De Caterina R, Fox KA, Halvorsen S, Huber K, Hylek EM, Lip GY, Montalescot G, Morais J, Patrono C, Verheugt FW, Wallentin L, Weiss TW, Storey RF, ESC Thrombosis Working Group. Antithrombotic therapy in the elderly: expert position paper of the European Society of Cardiology Working Group on Thrombosis. Eur Heart J 2015; 36: 3238 - 324

141. Kirchhof P, Benussi S, Kotecha D et al. 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. The Task Force for the management of atrial fibrillation of the European Society of Cardiology (ESC). Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC. Endorsed by the European Stroke Organisation (ESO). Eur Heart J 2016; 37: 2893 - 2962

142. Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet 2009; 373: 1849 - 60

143. Guirguis-Blake JM, Evans CV, Senger CA, O"Connor EA, Whitlock EP. Aspirin for the primary prevention of cardiovascular events: a systematic evidence review for the U.S. Preventive Services Task Force. Ann Intern Med. 2016; 164(12): 804 - 13

144. Antithrombotic Trialists" Collaboration Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients BMJ. 2002; 324(7329): 71 - 86.

145. Palmerini T, Della Riva D, Benedetto U et al. Three, six, or twelve months of dual antiplatelet therapy after DES implantation in patients with or without acute coronary syndromes: an individual patient data pairwise and network meta-analysis of six randomized trials and 11 473 patients. Eur Heart J. 2017; 38(14): 1034 - 1043.

146. Zhao G, Zhou M, MaC et al. In-Hospital Outcomes of Dual Loading Antiplatelet Therapy in Patients ars and Older With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Findings From the CCC-ACS (Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome) Project. J Am Heart Assoc. 2018; 7(7):e008100.

147. Bhatt DL, Fox KA, Hacke W, et al. Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events. N Engl J Med 2006; 354: 1706 - 17

148. Montalescot G, van 't Hof AW, Lapostolle F, Silvain J, Lassen JF, Bolognese L, Cantor WJ, Cequier A, Chettibi M, Goodman SG, Hammett CJ, Huber K, Janzon M, Merkely B, Storey RF, Zeymer U, Stibbe O, Ecollan P, Heutz WM, Swahn E, Collet JP, Willems FF, Baradat C, Licour M, Tsatsaris A, Vicaut E, Hamm CW, ATLANTIC Investigators. Prehospital ticagrelor in ST-segment elevation myocardial infarction. N Engl J Med 2014; 371(11): 1016 - 1027.

149. Wallentin L, Becker RC, Budaj A, Cannon CP, Emanuelsson H, Held C, Horrow J, Husted S, James S, Katus H, Mahaffey KW, Scirica BM, Skene A, Steg PG, Storey RF, Harrington RA, PLATO Investigators Freij A, Thorsen M. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med 2009; 361(11): 1045 - 1057

150. Sanchez PL, Gimeno F, Ancillo P, et al. Role of the paclitaxel-eluting stent and tirofiban in patients with ST-elevation myocardial infarction undergoing postfibrinolysis angioplasty: the GRACIA-3 randomized clinical trial. Circ Cardiovasc Interv 2010; 3(4): 297 - 307

151. Sonawane S, Kasbekar N, Bers JS. The safety of heparins in end-stage renal disease. Semin Dial. 2006 Jul-Aug; 19(4): 305 - 10.

152. Lazrak HH, 00000013.wmz 00000014.wmz, Elftouh N, Leblanc M, Lafrance JP. Safety of low-molecular-weight heparin compared to unfractionated heparin in hemodialysis: a systematic review and meta-analysis. BMC Nephrol. 2017 Jun 7; 18(1):187. doi: 10.1186/sl2882-017-0596-4.

153. US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, Curry SJ, Davidson KW, Epling JW Jr, 00000015.wmz FA, Gillman MW, Kemper AR, Krist AH, Kurth AE, Landefeld CS, LeFevre ML, Mangione CM, Phillips WR, Owens DK, Phipps MG, Pignone MP. Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2016; 316(19): 1997 - 2007.

154. Savarese G, Gotto AM Jr, Paolillo S, et al. Benefits of statins in elderly subjects without established cardiovascular disease: a meta-analysis. J Am Coll Cardiol. 2013; 62: 2090 - 9.

155. Teng M, Lin L, Zhao YJ, et al. Statins for primary prevention of cardiovascular disease in elderly patients: systematic review and meta-analysis. Drugs Aging. 2015; 32: 649 - 61.

156. Kutner JS, Blatchford PJ, Taylor DH Jr, et al. Safety and benefit of discontinuing statin therapy in the setting of advanced, life-limiting illness: a randomized clinical trial. JAMA

157. Ponikowski P, Voors AA, Anker SD et al. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. Eur Heart J. 2016. 37: 2129 - 200

158. Gorodeski EZ, Goyal P, Hummel SL et al. Domain Management Approach to Heart Failure in the Geriatric Patient. Present and Future. J Am Coll Cardiol 2018; 71: 1921 - 36)

159. Hopper I, Samuel R, Hayward C, Tonkin A, Krum H. Can medications be safely withdrawn in patients with stable chronic heart failure? Systematic review and meta-analysis. J Card Fail 2014; 20: 522 - 32.

160. Komajda M, Hanon O, Hochadel M et al. Contemporary management of octogenarians hospitalized for heart failure in Europe: Euro Heart Failure Survey II. European Heart Journal. 2009; 30: 478 - 486

161. Burnett H, Earley A, Voors AA et al. Thirty Years of Evidence on the Efficacy of Drug Treatments for Chronic Heart Failure With Reduced Ejection Fraction: A Network Meta-Analysis. Circ Heart Fail. 2017 Jan; 10(1): e003529

162. Дедов И.И., Шеставков М.В., Галстян Г.Р. и др. Алгоритмы специализированной медицинской помощи больным сахарным диабетом/под ред. И.И. Дедова, М.В. Шестаковой; 8-й вып.//Сахарный диабет. 2017; 20(1S): 1 - 121

163. Wiener DC, Larson RJ. Benefits and risks of tight glucose control in critically ill adults: a meta-analysis. JAMA. 2008; 300(8): 933 - 44.

164. Huang ES, Laiteerapong N, Liu JY, John PM, Moffet HH, Karter AJ, et al. Rates of complications and mortality in older patients with diabetes mellitus: the diabetes and aging study. JAMA Intern Med 2014; 174: 251 - 25

165. Duckworth W, Abraira C, Moritz T, Reda D, Emanuele N, Reaven P, Zeive FJ, Marks J, David SN, Hayward R, Warren SR, Goldman S, McCarren M, Vitek ME, Henderson WG, Huang GD. Glucose control and vascular complications in veterans with type 2 diabetes. N Eng J Med 2009. 360(2): 129 - 139.

166. Ismail-Beigi F, Craven T, Banerji MA, et al. ACCORD trial group Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 2010; 376: 419 - 430

167. Yaffe K, Falvey C, Hamilton N, et al. Diabetes, glucose control, and 9-year cognitive decline among older adults without dementia. Arch Neurol 2012; 69: 1170 - 1175

168. Launer LJ, Miller ME, Williamson JD, et al.; ACCORD MIND Investigators. Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): a randomised open-label substudy. Lancet Neurol 2011; 10: 969 - 977

169. Munshi MN, Pandya N, Umpierrez GE, et al. Contributions of basal and prandial hyperglycemia to total hyperglycemia in older and younger adults with type 2 diabetes mellitus. J Am Geriatr Soc 2013; 61: 535 - 41

170. Moore E, Mander A, Ames D, Carne R, Sanders K, Watters D. Cognitive impairment and vitamin B12: a review. Int Psychogeriatr. 2012; 24(4): 541 - 56.

171. Sorbi S, Hort J, Erkinjuntti T, Fladby T, Gainotti G, Gurvit H, Nacmias B, Pasquier F, Popescu BO, Rektorova I, Religa D, Rusina R, Rossor M, Schmidt R, Stefanova E, Warren JD, Scheltens P; EFNS Scientist Panel on Dementia and Cognitive Neurology. EFNS-ENS Guidelines on the diagnosis and management of disorders associated with dementia. Eur J Neurol. 2012; 19(9): 1159 - 79

172. Ngo J, Holroyd-Leduc JM. Systematic review of recent dementia practice guidelines. Age Ageing. 2015; 44(1): 25 - 33.

173. Wirth Y, Goebel C. Memantine in patients with moderate to severe Alzheimer"s disease: meta-analyses using realistic definitions of response Dement Geriatr Cogn Disord. 2014; 37(1-2): 71 - 85

174. Molino I, Colucci L, Fasanaro AM, Traini E, Amenta F. Efficacy of memantine, donepezil, or their association in moderate-severe Alzheimer"s disease: a review of clinical trials. Scientific World Journal. 2013; 2013: 925702

175. Chen YD, Zhang J, Wang Y, Yuan JL, Hu WL. Efficacy of Cholinesterase Inhibitors in Vascular Dementia: An Updated Meta-Analysis. Eur Neurol. 2016; 75(3-4): 132 - 41.

176. Di Santo SG, Prinelli F, Adorni F, Caltagirone C, Musicco M. A meta-analysis of the efficacy of donepezil, rivastigmine, galantamine, and memantine in relation to severity of Alzheimer"s disease. J Alzheimers Dis. 2013; 35(2): 349 - 61.

177. Rountree SD, Atri A, Lopez OL, Doody RS. Effectiveness of antidementia drugs in delaying Alzheimer"s disease progression. Alzheimers Dement. 2013 May; 9(3): 338 - 45.

178. Masopust J, 00000016.wmz D, 00000017.wmz M, Pavelek Z, 00000018.wmz B. Treatment of behavioral and psychological symptoms of dementias with psychopharmaceuticals: a review. Neuropsychiatr Dis Treat. 2018; 14: 1211 - 1220

179. Bridle C, Spanjers K, Patel S, Atherton NM, Lamb SE. Effect of exercise on depression severity in older people: systematic review and meta-analysis of randomised controlled trials. Br J Psychiatry. 2012; 201: 180 - 185.

180. Dickens AP, Richards SH, Greaves CJ, Campbell JL. Interventions targeting social isolation in older people: a systematic review. BMC Public Health. 2011; 11: 647

181. Cruwys T, Dingle GA, Haslam C, Haslam SA, Jetten J, Morton TA. Social group memberships protect against future depression, alleviate depression symptoms and prevent depression relapse. Soc Sci Med. 2013; 98: 179 - 186.

182. Forsman AK, Schierenbeck I, Wahlbeck K. Psychosocial interventions for the prevention of depression in older adults: systematic review and meta-analysis. J Aging Health. 2011; 23: 387 - 416.

183. Alamo C, 00000019.wmz F, 00000020.wmz P, 00000021.wmz S. Risk-benefit analysis of antidepressant drug treatment in the elderly. Psychogeriatrics. 2014; 14(4): 261 - 8.

184. Sultana J, Spina E, 00000022.wmz G. Antidepressant use in the elderly: the role of pharmacodynamics and pharmacokinetics in drug safety/Expert Opin Drug Metab Toxicol. 2015 Jun; 11(6): 883 - 92.

185. MacQueen G.M., Frey B.N., Ismail Z. et al Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder/Canadian journal of psychiatry. - 2016. - Vol. 61(9). - P. 588 - 603.

186. 00000023.wmz J, van der Mast RC, Vandenberghe J3, Van Den Eede F Efficacy and Tolerability of Atypical Antipsychotics in the Treatment of Delirium: A Systematic Review of the Literature. Psychosomatics. 2018. pii: S0033-3182(18)30258-5.

187. Rastogi R, Meek BD. Management of chronic pain in elderly, frail patients: finding a suitable, personalized method of control. Clin Interv Aging. 2013; 8: 37 - 4

188. American Geriatrics Society Panel on the Pharmacological Management of Persistent Pain in Older Persons. Pharmacological management of persistent pain in older persons. J Am Geriatr Soc. 2009; 57(8): 1331 - 1346.

189. Каратеев АЕ, Насонов ЕЛ, Яхно НН и др. Клинические рекомендации "Рациональное применение нестероидных противовоспалительных препаратов (НПВП) в клинической практике". Современная ревматология. 2015; (1): 4 - 23

190. Оганов Р.Г., Ткачева О.Н. и соавт. Коморбидная патология в клинической практике. Клинические рекомендации. Кардиоваскулярная терапия и профилактика. 2017; 16 (6): 5 - 56.

191. Wehling, Martin F. "Non-steroidal anti-inflammatory drug use in chronic pain conditions with special emphasis on the elderly and patients with relevant comorbidities: management and mitigation of risks and adverse effects." European Journal of Clinical Pharmacology 70 (2014): 1159 - 1172.

192. C.M Williams, C.G. Maher, J. Latimer, A.J. McLachlan, M.J. Hancock, R.O. Day, C.-W. C. Lin. Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. Lancet. 2014; 384 (9954).

193. Bischoff-Ferrari HA, Willett WC, Wong JB, et al. Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med. 2009; 169(6): 551 - 61;

194. Mushtaq S, Choudhary R, Scanzello CR. Non-surgical treatment of osteoarthritis-related pain in the elderly. Curr Rev Musculoskelet Med. 2011; 4(3): 113 - 22.

195. Остеопороз. Клинические рекомендации Российской ассоциации по остеопорозу/Под ред. О.М. Лесняк, Л.И. Беневоленской. - М.: ГЭОТАР-Медиа, 2009.

196. Prather H, Watson JO, Gilula LA. Nonoperative management of osteoporotic vertebral compression fractures. Injury. 2007 Sep. 38 Suppl 3:S40-8

197. Freedman BA, Potter BK, Nesti LJ, et al. Osteoporosis and vertebral compression fractures-continued missed opportunities. The Spine Journal: official journal of the North American Spine Society. 2008 Sep-Oct; 8(5): 756 - 62

198. Singh J.A., Noorbaloochi S., MacDonald R., Maxwell L.J. The Cochrane Collaboration Chondroitin for osteoarthritis. Cochrane Libr, 2015

199. Zhang W, Nuki G, Moskowitz RW, Abramson S, Altman RD, Arden NK, et al. OARSI recommendations for themanagement of hip and knee osteoarthritis: part III: changes in evidence following systematic cumulative update of research published through January 2009. Osteoarthritis and Cartilage/OARS, Osteoarthritis Research Society 2010; 18(4): 476e99.

200. Towheed T, Maxwell L, Anastassiades TP, Shea B, Houpt J, Welch V, Hochberg MC, Wells GA. Glucosamine therapy for treating osteoarthritis. Cochrane Database of Systematic Reviews 2005, Issue 2. Art. No.: CD002946

201. Kongtharvonskul J., Anothaisintawee T., McEvoy M., Attia J., Woratanarat P., A. Thakkinstian. Efficacy and safety of glucosamine, diacerein, and NSAIDs in osteoarthritis knee: a systematic review and network meta-analysis. Eur J Med Res. 2015; 20(1): 24.

202. .Fidelix TS.A., Macedo CR, Maxwell LJ, Fernandes 00000024.wmz Trevisani V. Diacerein for osteoarthritis. Cochrane Database of Systematic Reviews 2014, Issue 2. Art. No.: CD005117.

203. Montgomery, S., Chatamra, K., Pauer, L., Whalen, E., & Baldinetti, F. (2008). Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. British Journal of Psychiatry, 193(5), 389 - 394.

204. Клинически рекомендации "Хронический болевой синдром (ХБС) у взрослых пациентов, нуждающихся в паллиативной медицинской помощи" (МЗ России). М.: 2016

205. Bruehl S, Apkarian AV, Ballantyne JC, et al. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. J Pain. 2013; 14(2): 103 - 13

206. Monteserin E, Brotons C, Moral I, Altimir S, San 00000025.wmz A, Santaeugenia S, et al. Effectiveness of a geriatric intervention in primary care: a randomized clinical trial. Fam Pract 2010; 27(3): 239 - 45.

207. Behm L, Eklund K, Wilhelmson K, Zide'n L, Gustafsson S, Falk K, et al. Health promotion can postpone frailty: Results from the RCT elderly persons in the Risk Zone. Public Health Nurs 2016; 33(4): 303 - 15.

208. Graf C Functional decline in hospitalized older adults. Am J Nurs 2006; 106:58.25

209. Flaherty JH. Insomnia among hospitalized older persons. Clin Geriatr Med 2008; 24:51.31.

210. Vaurio LE, Sands LP, Wang Y, et al. Postoperative delirium: the importance of pain and pain management. Anesth Analg 2006; 102: 1267.

211. Inouye SK, Bogardus ST Jr, Charpentier PA, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med 1999; 340:669. 33.

212. Corcoran PJ. Use it or lose it - the hazards of bed rest and inactivity. West J Med 1991; 21.154: 536.

213. Girard TD. Crit Care Clin. 2018; 34(4): 585 - 598

214. Surkan MJ, Gibson W. Interventions to Mobilize Elderly Patients and Reduce Length of Hospital Stay. Can J Cardiol. 2018; 34(7): 881 - 888

215. Van Grootven B, McNicoll L, Mendelson DA, Friedman SM, Fagard K, Milisen K, Flamaing J, Deschodt M; G-COACH consortium. Quality indicators for in-hospital geriatric co-management programmes: a systematic literature review and international Delphi study. BMJ Open. 2018; 8(3): e020617.

216. Guirguis-Blake JM, Michael YL, Perdue LA, Coppola EL, Beil TL. Interventions to Prevent Falls in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA. 2018; 319(16): 1705 - 171

217. Porter-Armstrong AP, Moore ZE, Bradbury I, McDonough S. Education of healthcare professionals for preventing pressure ulcers. Cochrane Database Syst Rev. 2018 May 25; 5: CD011620